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Obesity is a disease that affects millions of American adults, adolescents, and children, posing serious health risks. Phentermine is a weight loss pill. Medical professionals generally consider obesity to be a chronic illness requiring life-long treatment and management. It is often grouped with other chronic conditions, such as high blood pressure and diabetes. Phentermine is a stimulant that is similar to an amphetamine.This medicine can help you reduce weight or maintain a lower weight by suppressing your appetite. Phentermine is a centrally-acting appetite suppressant that is used as a weight control medication. Phentermine is an appetite suppressant that affects the central nervous system.It is indicated for the management of obesity.The medicine was used from 2 weeks to 24 weeks, with an average use of about 13 weeks. In the studies reviewed, most of the people using phentermine also made lifestyle changes, such as diet or exercise. Taking phentermine together with other diet medications such as fenfluramine or dexfenfluramine can cause a rare fatal lung disorder called pulmonary hypertension. Do not take phentermine with any other diet medications is not indicated so you should ask your personal doctor before taking it. Phentermine is used togther with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.Weight loss varies depending on how long the medicine is taken. A review of research reports that using 15 to 30 mg of phentermine daily resulted in an average weight loss of about 8 lb (3.6 kg) more than when taking a placebo. Phentermine comes in tablets and extended-release capsules. It usually is taken as a single daily dose in the morning or three times a day 30 minutes before meals. It is not known whether phentermine will harm an unborn baby. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take phentermine exactly as directed. Do not take phentermine without first talking to your doctor if you are pregnant. It is also not known whether phentermine passes into breast milk or if it could harm a nursing baby. Do not give this medication to anyone younger than 16 years old without the advice of a doctor. Do not take phentermine without first talking to your doctor if you are breast-feeding a baby. If you miss a dose of phentermine you should take the missed dose as soon as you remember it. And, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one, it will not supply the missed dose. If you decide to buy phentermine you should keep this medication in the container it came in, tightly closed, and out of reach of children. Phentermine should be stored in, at room temperature and away from excess heat and moisture (recomanded not in the bathroom). If you have phentermine that are outdated or no longer needed throw away any medication. You should check online about the proper disposal of your medication.
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Taking phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take phentermine with any other diet medications without your doctor's advice. Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. It is best to take phentermine on an empty stomach before breakfast, or at least 10 to 14 hours before bedtime. Do not take more phentermine for an increased effect. Taking too much of this medication can cause serious, life-threatening side effects. Do not crush, chew, break, or open an extended-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time. Phentermine is available with a prescription under the brand names Phentermine, Adipex and Fastin. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you. After you have taken Phentermine for a few weeks, it will usually not work as well as when you began taking it. This is known at TOLERANCE. Talk with your doctor if Phentermine stops working well. Do not take more medicine than prescribed. Some people who use Phentermine for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking Phentermine suddenly, you may have WITHDRAWAL symptoms. These may include extreme tiredness, mental depression, trouble sleeping, irritability, or mental, mood, or personality changes. Phentermine is used in combination with a healthy diet, physical exercise and lifestyle changes to reduce body weight in patients who are obese. It functions as an appetite suppressant but should only be used for short periods of time. The combination of fenfluramine and phentermine was a widely used obesity treatment before the withdrawal of fenfluramine for an association with heart valve regurgitation. The prevalence and clinical significance of regurgitation among patients treated with these medications has yet to be fully established. To evaluate the potential association between the duration of treatment and the prevalence of heart valve abnormalities, we examined 1163 patients who had taken fenfluramine-phentermine and 672 control patients who had not taken the drug combination within 5 years. Mild or greater aortic regurgitation was present in 8.8% of treated patients and 3.6% of control patients (P<0.001). Moderate or greater mitral regurgitation was present in 2.6% of treated patients and 1.5% of control patients (P=0.18). The adjusted odds ratio compared with controls of aortic regurgitation of mild or greater severity increased according to duration of treatment: 90 to 180 days, 1.5 (P=0.23); 181 to 360 days, 2.4 (P=0.002); 361 to 720 days, 4.6 (P<0.001); >720 days, 6.2 (P<0.001). This is the largest study to demonstrate a relation between the length of treatment with fenfluramine-phentermine and the prevalence of valvular abnormalities. These findings suggest that valvular abnormalities in patients who took fenfluramine-phentermine primarily involve those who had taken these medications for >6 months and predominantly results in mild aortic regurgitation. The valve regurgitation identified by this study was not accompanied by significant differences in cardiovascular symptoms nor physical findings other than a higher prevalence of heart murmurs.


